Anti-Wee1-like protein kinase 2 WEE2 Antibody

Primary Antibodies

62925 MW

WB: 1:500-1:1000

Wee1-like protein kinase 2

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

1 mg/ml

Oocyte-specific protein tyrosine kinase that
phosphorylates and inhibits CDK1 and acts as a key regulator of
meiosis during both prophase I and metaphase II. Required to
maintain meiotic arrest in oocytes during the germinal vesicle
(GV) stage, a long period of quiescence at dictyate prophase I, by
phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity
and prevent meiotic reentry. Also required for metaphase II exit
during egg activation by phosphorylating CDK1 at 'Tyr-15', to
ensure exit from meiosis in oocytes and promote pronuclear
formation (By similarity).

Boster Bio Anti-Wee1-like protein kinase 2 WEE2 Antibody catalog # A10843-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.