Anti-Wee1-like protein kinase 2 WEE2 Antibody

Rabbit IgG

62925 MW

Western Blot, 1:500 - 1:2000
ELISA, 1:5000
Not yet tested in other applications.

Wee1-like protein kinase 2

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).

Boster Bio Anti-Wee1-like protein kinase 2 WEE2 Antibody (Catalog# A10843). Tested in WB, ELISA applications. This antibody reacts with Human, Rat, Mouse.

Expressed in testis.