Anti-Kallikrein 10/KLK10 Antibody Picoband®

Primary Antibodies

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

30170 MW

Western blot, 0.1-0.5?g/ml, Human, Rat

Kallikrein-10

KLK10 (kallikrein-related peptidase 10) also known as kallikrein 10, PRSSL1 or NES1, belongs to the kallikrein subfamily of serine proteases, which are involved in a variety of enzymatic processes. Its encoded protein is secreted and may play a role in suppression of tumorigenesis  in  breast  and  prostate cancers.KLK10  also contains 12 conserved cysteines in its protease domain that are expected to form 6 disulfide bonds, as in other serine proteases.  RT-PCR detected variable levels of  KLK10  expression in nearly all of the 35 adult and fetal tissues examined. The  KLK10  gene contains 6 exons, the first of which is noncoding. By fluorescence in situ hybridization,   Polikoff et al. (1997)  mapped the PRSSL1 gene to 19q13.3. By genomic sequence analysis,   Gan et al. (2000)  mapped the  KLK10  gene within the KLK gene cluster on chromosome 19q13. This cluster includes 13 KLK genes and 5 pseudogenes.

Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.

Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.

Cancer, Cell Biology, Cytoskeleton/ECM, ECM Enzymes, Extracellular Matrix, Invasion/Microenvironment, Proteolysis/Ubiquitin, Proteolytic Enzymes, Signal Transduction

Has a tumor-suppressor role for NES1 in breast and prostate cancer.

Boster Bio Anti-Kallikrein 10/KLK10 Antibody catalog # PA1821. Tested in WB applications. This antibody reacts with Human, Rat.

Belongs to the peptidase S1 family. Kallikrein subfamily.