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Anti-Prolactin/PRL Antibody Picoband®

Anti-Prolactin/PRL Antibody Picoband®

Item no.	BOS-PB9361
Manufacturer	Boster
Amount	100 ug/vial
Category	Oncology Food Safety Allergenes Antibodies By Cell Type Hematology Leukemia Lymphoma Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Format	Lyophilized
Applications	WB, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Sensitivity	<5pg/ml
Citations	1. Correale J, et al. Role of prolactin in B cell regulation in multiple sclerosis. J Neuroimmunol, 2014 Apr 15. 2. De Kuijper GM, et al. Effects of discontinuation of long-term used antipsychotics on prolactin and bone turnover markers in patients with intellectual disability. J Clin Psychopharmacol, 2014 Feb. 3. Zaga-Clavellina V, et al. The potential role of prolactin as a modulator of the secretion of proinflammatory mediators in chorioamniotic membranes in term human gestation. Am J Obstet Gynecol, 2014 Jul.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Prolactin;PRL;PRL;
Available
Specificity	No cross reactivity with other proteins.
Manufacturer - Category	Primary Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	25 kDa
Calculated Molecular weight	25876 MW
Clonality	Polyclonal
Application Details	Western blot, 0.1-0.5?g/ml, Human, - ELISA, 0.1-0.5?g/ml, -
Manufacturer - Gene Name	PRL
Gene Full Name	Prolactin
Manufacturer - Specificity	No cross reactivity with other proteins.
Background	Prolactin (PRL), also known as luteotropic hormone or luteotropin, is a protein that in humans is best known for its role in enabling female mammals to produce milk. This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein.
Immunogen	E.coli-derived human Prolactin recombinant protein (Position: L29-227C). Human Prolactin?shares?60%?and 63% amino?acid?(aa)?sequence?identity?with mouse?and?rat Prolactin, respectively.
Contents	Each vial contains 5 mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05 mg NaN3.
Purification	Immunogen affinity purified.
Reconstitution	Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category	Growth Factors/Hormones, Lipid Metabolism, Metabolism, Protein Phosphorylation, Receptor Tyrosine Kinases, Signal Transduction, Tyrosine Kinases
Protein Name	Prolactin
Protein Function	Prolactin acts primarily on the mammary gland by promoting lactation.
Subcellular Localization	Secreted.
Description	Boster Bio Anti-Prolactin/PRL Antibody Picoband® catalog # PB9361. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Tissue Specificity	Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone- independent mammary carcinoma cell lines.
Sequence Similarities	Belongs to the somatotropin/prolactin family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-PB9361-datasheet.pdf

BOS-PB9361-safety-datasheet.pdf