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Anti-C-X-C motif chemokine 16 CXCL16 Antibody Picoband® European Partner

Item no. BOS-PA1460
Manufacturer Boster
Amount 100 ug/vial
Category
Type Antibody Polyclonal
Format Lyophilized
Applications WB, IHC
Specific against Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Sensitivity <10pg/ml
Citations 1. Matloubian, M., David, A., Engel, S., Ryan, J. E., Cyster, J. G.A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo.Nature Immun. 1: 298-304, 2000.
2. Shimaoka, T., Kume, N., Minami, M., Hayashida, K., Kataoka, H., Kita, T., Yonehara, S.Molecular cloning of a novel scavenger receptor for oxidized low absorbance lipoprotein, SR-PSOX, on macrophages.J. Biol. Chem. 275: 40663-40666, 2000.
3. Wilbanks, A., Zondlo, S. C., Murphy, K., Mak, S., Soler, D., Langdon, P., Andrew, D. P., Wu, L., Briskin, M.Expression cloning of the STRL33/BONZO/TYMSTR ligand reveals elements of CC, CXC, CX3C chemokines.J. Immun. 166: 5145-5154, 2001.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias C-X-C motif chemokine 16;Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein;SR-PSOX;Small-inducible cytokine B16;Transmembrane chemokine CXCL16;Cxcl16;Srpsox;
Similar products Chemokine, CXC motif, C-X-C motif chemokine 16 antibody, Chemoki(C X C motif) ligand 16 antibody, ligand 16 antibody, CXC chemokine ligand 16 antibody, Cxcl16 antibody, CXCLG16 antibody, CXL16_HUMAN antibody, Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein antibody, SCYB16 antibody, Small inducible cytokine B16 precursor antibody, Small-inducible cytokine B16 antibody, SR-PSOX antibody, SRPSOX antibody, Transmembrane chemokine CXCL16 antibody, UNQ2759/PRO6714 antibody
Available
Manufacturer - Category
Primary Antibodies
Manufacturer - Isotype
Rabbit IgG
Storage Conditions
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight
26-35 kDa
Calculated Molecular weight
26896 MW
Clonality
Polyclonal
Application Details
Immunohistochemistry (Paraffin-embedded Section), 0.5-1?g/ml, Mouse, By Heat

Western blot, 0.1-0.5?g/ml, Mouse
Manufacturer - Gene Name
CXCL16
Gene Full Name
C-X-C motif chemokine 16
Manufacturer - Specificity
No cross reactivity with other proteins.
Background
CXCL16, Chemokine (C-X-C motif) ligand 16, is a small cytokine belonging to the CXC chemokine family. Larger than other chemokines (with 254 amino acids ), CXCL16 is composed of a CXC chemokine domain, a mucin-like stalk, a transmembrane domain and a cytoplasmic tail containing a potential tyrosine phosphorylation site that may bind SH2. By somatic cell hybrid analysis, the CXCL16 gene is mapped to 17p13, a locus separate from all other known chemokines. Chemotaxis assays found that CXCL16 induced a strong chemotactic response in activated CD8 T cells. In addition, CXCL16 induced calcium mobilization.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of mouse CXCL16.
Contents
Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2mg Na2HPO4.
Purification
Immunogen affinity purified.
Reconstitution
Add 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 ?g/ml.
Manufacturer - Research Category
Chemokines, Immunology, Innate Immunity, Macrophage/Inflammation
Protein Name
C-X-C motif chemokine 16
Protein Function
Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Also acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis.
Subcellular Localization
Membrane; Single-pass type I membrane protein.
Description
Boster Bio Anti-C-X-C motif chemokine 16 CXCL16 Antibody catalog # PA1460. Tested in IHC, WB applications. This antibody reacts with Mouse.
Tissue Specificity
Widely expressed. Not detected in purified B- and T-cells.
Sequence Similarities
Belongs to the SFTPA family.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug/vial
Available: In stock
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