Anti-XPA Antibody

Item no.	BOS-A01182
Manufacturer	Boster
Amount	100 ul
Category	Metabolism Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody
Format	Liquid
Applications	WB, IHC
Specific against	Human (Homo sapiens)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DNA repair protein complementing XP-A cells;Xeroderma pigmentosum group A-complementing protein;XPA;XPAC;
Available
Manufacturer - Category	Primary Antibodies
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	31368 MW
Clonality	Polyclonal
Application Details	Western blotting: 1:500~1:3000 Immunohistochemistry: 1:50~1:100
Manufacturer - Gene Name	XPA
Gene Full Name	DNA repair protein complementing XP-A cells
Background	Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation. Gary W. Daughdrill, Nucleic Acids Res., Jul 2003; 31: 4176 - 4183. Esther M. Hoogervorst, Carcinogenesis, Mar 2003; 24: 613 - 619. Karen M. Vasquez, PNAS, Apr 2002; 99: 5848.
Immunogen	Synthesized peptide derived from Internal of human XPA.
Contents	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration	1 mg/ml
Manufacturer - Research Category	DNA/RNA, DNA Damage & Repair, Epigenetics and Nuclear Signaling
Protein Function	Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.
Subcellular Localization	Nucleus.
Short Description	Boster Bio Anti-XPA Antibody (Catalog # A01182). Tested in WB, IHC applications. This antibody reacts with Human.
Description	Boster Bio Anti-XPA Antibody (Catalog # A01182). Tested in WB, IHC applications. This antibody reacts with Human.
Tissue Specificity	Expressed in various cell lines and in skin fibroblasts.

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BOS-A01182-datasheet.pdf

BOS-A01182-safety-datasheet.pdf