Manufacturer |
Boster
|
Category |
|
Type |
Antibody Primary |
Specific against |
Mouse, Rat |
Isotype |
IgG |
Format |
Lyophilized |
Applications |
WB, IHC, ELISA |
Amount |
100 ug/vial |
Host |
Rabbit |
Item no. |
BOS-A01787-1 |
Targets |
AREG |
eClass 6.1 |
32160702 |
eClass 9.0 |
32160702 |
Available |
|
Manufacturers Product Category |
Primary Antibodies, Rabbit Polyclonal Antibodies |
Manufacturers Research Category |
Signal Transduction |
Short Description |
Boster Bio Anti-Amphiregulin/Areg Antibody Picoband™ catalog # A01787-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. |
Description |
Boster Bio Anti-Amphiregulin/Areg Antibody Picoband™ catalog # A01787-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. |
Background |
Amphiregulin, also known as AREG, is a protein that in humans is encoded by the AREG gene. The protein encoded by this gene is a member of the epidermal growth factor (EGF) family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the Epidermal growth factor receptor (EGFR) to promote the growth of normal epithelial cells. It is mapped to 9q32. It has been shown to play a role in immunity, inflammation, tissue repair, and lung and mammary gland development. Homozygous knockout mice for this gene exhibit impaired immune system regulation in the skin and gene expression changes characteristic of chronic liver damage. |
Gene Name |
AREG |
Application Details |
Western blot, 0.1-0.5μg/ml Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml ELISA (Cap), 1-5μg/ml |
Clonality |
Polyclonal |
Concentration |
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
Contents |
Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. |
Immunogen |
E. coli-derived mouse Amphiregulin recombinant protein (Position:V100-K191). |
Cross-reactivity |
No cross-reactivity with other proteins. |
Storage |
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles. |
Reconstitution |
Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Gene Full Name |
amphiregulin |
Molecular Weight |
41 kDa |
Protein Function |
Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts. |
Subcellular Localization |
Membrane; Single-pass membrane protein. |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.