« Back
Home /
Anti-RNase III Drosha Antibody

Anti-RNase III Drosha Antibody

Manufacturer	Boster
Category	Oncology Neuroscience Metabolism Cholesterol & Lipid Metabolism Neural Epigenetics Antibodies Western Blot Primary Antibodies By Organ Heart & Blood Cancer
Type	Antibody
Specific against	Human, Mouse
Isotype	IgG
Format	Liquid
Applications	WB, IF, ELISA, IHC-P
Amount	100ul
Host	Rabbit
Item no.	BOS-A19835
Targets	DROSHA
eClass 6.1	32160702
eClass 9.0	32160702
Available
Manufacturers Product Category	Primary Antibodies
Manufacturers Research Category	DNA/RNA, Epigenetics and Nuclear Signaling, Nuclear Receptors, Nuclear Signaling Pathways, RNA Processing
Short Description	Boster Bio Anti-RNase III Drosha Antibody (Catalog# A19835). Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse.
Description	Boster Bio Anti-RNase III Drosha Antibody (Catalog# A19835). Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse.
Gene Name	DROSHA
Clonality	Polyclonal
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Contents	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Application Details	Western Blot, 1:500 - 1:2000 IHC-P, 1:100-1:300 ELISA, 1:10000 Not yet tested in other applications.
Immunogen	A peptide derived from human RNase III Drosha. Immunogen sequence location: 774 - 823
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Storage	Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name	Ribonuclease 3
Molecular Weight	159316 MW
Protein Function	Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA- ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double- strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.
Subcellular Localization	Nucleus. Nucleus, nucleolus. A fraction is translocated to the nucleolus during the S phase of the cell cycle. Localized in GW bodies (GWBs), also known as P-bodies.
Tissue Specificity	Ubiquitous.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100ul

available

Delivery expected until 5/30/2024