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Anti-GPR120 FFAR4 Antibody

Anti-GPR120 FFAR4 Antibody

Manufacturer	Boster
Category	Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies Obesity Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody
Specific against	Human, Mouse, Rat
Isotype	IgG
Format	Liquid
Applications	WB, IF, ICC, ELISA
Amount	100ul
Host	Rabbit
Item no.	BOS-A19859
Targets	FFAR4
eClass 6.1	32160702
eClass 9.0	32160702
Available
Manufacturers Product Category	Primary Antibodies
Short Description	Boster Bio Anti-GPR120 FFAR4 Antibody (Catalog# A19859). Tested in WB, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Description	Boster Bio Anti-GPR120 FFAR4 Antibody (Catalog# A19859). Tested in WB, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.
Gene Name	FFAR4
Clonality	Polyclonal
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Contents	PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Application Details	Western Blot, 1:500 - 1:2000 Immunofluorescence, 1:200 - 1:1000 ELISA, 1:5000 Not yet tested in other applications.
Immunogen	A peptide derived from human GPR120. Immunogen sequence location: 221 - 270
Purification	The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Storage	Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name	Free fatty acid receptor 4
Molecular Weight	42241 MW
Protein Function	Receptor for medium and long-chain free fatty acids (FFAs). Signals via a G (q)/G (11)-coupled pathway. Acts as a receptor for omega-3 fatty acids and mediates robust anti- inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects involve inhibition of TAK1 through a beta-arrestin 2 (ARRB2)/TAB1-dependent effect, but independent of the G (q)/G (11)-coupled pathway. Mediates potent insulin sensitizing and antidiabetic effects by repressing macrophage- induced tissue inflammation. May mediate the taste of fatty acids. Mediates FFA-induced inhibition of apoptosis in enteroendocrine cells. May play a role in the regulation of adipocyte development and differentiation.
Subcellular Localization	Cell membrane; Multi-pass membrane protein. Colocalized with ARRB2 following DHA treatment.
Tissue Specificity	Abundant expression in the intestinal tract. Highly expressed in adipose tissue, small intestine and pancreas.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ul

available

Delivery expected until 5/30/2024