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Anti-CD41 ITGA2B Rabbit Monoclonal Antibody

Anti-CD41 ITGA2B Rabbit Monoclonal Antibody

Item no.	BOS-M01102
Manufacturer	Boster
Amount	100 ul
Category	Food Safety Proteins Antibodies Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid
Applications	WB, IHC
Clone	AAGH-9
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Sensitivity	<10pg/ml
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Integrin alpha-IIb;GPalpha IIb;GPIIb;Platelet membrane glycoprotein IIb;CD41;Integrin alpha-IIb heavy chain;Integrin alpha-IIb light chain, form 1;Integrin alpha-IIb light chain, form 2;ITGA2B;GP2B, ITGAB;
Available
Manufacturer - Category	Rabbit Monoclonal Antibodies
Manufacturer - Isotype	Rabbit IgG
Storage Conditions	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Observed Molecular Weight	110 kDa
Calculated Molecular weight	113377 MW
Clonality	Monoclonal
Application Details	WB 1:500-1:1000 IHC 1:50-1:200
Manufacturer - Gene Name	ITGA2B
Gene Full Name	Integrin alpha-IIb
Immunogen	A synthesized peptide derived from human CD41
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.
Purification	Affinity-chromatography
Reconstitution	Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Manufacturer - Research Category	Angiogenesis, Cardiovascular, Cell Adhesion, Cell Type Markers, Cytoskeleton/ECM, Hematopoietic Progenitors, Immunology, Integrins, Myeloid, Platelets, Signal Transduction, Stem Cells
Protein Name	Glycogen synthase kinase-3 beta (gsk3b)
Protein Function	Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha- IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.
Subcellular Localization	Membrane; Single-pass type I membrane protein.
Description	Boster Bio Anti-CD41 ITGA2B Rabbit Monoclonal Antibody catalog # M01102. Tested in WB, IHC applications. This antibody reacts with Human.
Tissue Specificity	Isoform 1 and isoform 2 were identified in platelets and megakaryocytes, but not in reticulocytes or in Jurkat and U-937 white blood cell line. Isoform 3 is expressed by leukemia, prostate adenocarcinoma and melanoma cells but not by platelets or normal prostate or breast epithelial cells.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

BOS-M01102-datasheet.pdf

BOS-M01102-safety-datasheet.pdf