Anti-PHOX2B Monoclonal Antibody

Rabbit Monoclonal Antibodies

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

57235 MW

WB 1:500-1:2000
IHC 1:100-1:500
ICC/IF 1:50-1:200

CD276 antigen

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5 mg/ml BSA.

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Developmental Families, Domain Families, Epigenetics and Nuclear Signaling, Neural Signal Transduction, Neurogenesis, Neurology Process, Neuroscience, Transcription

May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.

Boster Bio Anti-PHOX2B Monoclonal Antibody catalog # M02221. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse.