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MECP2 Methyl CpG Binding Protein 2 Human Recombinant Protein

MECP2 Methyl CpG Binding Protein 2 Human Recombinant Protein

Manufacturer	Boster
Category	Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Epigenetics Peptides & Proteins Recombinant Proteins Glial Cell Markers
Type	Proteins Recombinant
Specific against	other
Format	Solution
Amount	10ug
Item no.	BOS-PROTP51608
Targets	MECP2
eClass 6.1	34160400
eClass 9.0	42020190
Available
Description	MECP2 Human Recombinant is expressed in 293 cells. The protein contains 486 amino acids (1-486a.a.) and fused to an N-terminal Flag tag, having an Mw of 53.56kDa.
Gene name	MECP2
Protein function	Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
Purification	Greater than 80% as determined by SDS-PAGE.
Shipping	Shipped with wet ice
Short description	MECP2 Human Recombinant is expressed in 293 cells. The protein contains 486 amino acids (1-486a.a.) and fused to an N-terminal Flag tag, having an Mw of 53.56kDa.
Storage	Store in -20° C for long term storage. After reconstitution, store in 4° C for short term usage within a few days. Avoid freeze-thaw cycles.
Subcellular localization	Nucleus. Colocalized with methyl-CpG in the genome.
Tissue specificity	Present in all adult somatic tissues tested.
Format Information	Sterile Filtered colorless solution.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10ug

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