« Back
Home /
Rabbit Anti-Human APAF1 Affinity Purified pAb

Rabbit Anti-Human APAF1 Affinity Purified pAb

Manufacturer	Cell Sciences
Category	Antibodies Cell Biology Cell Status Apoptosis Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Human
Isotype	IgG
Applications	WB
Amount	100 ug
Host	Rabbit
Item no.	CS-CPA103
Targets	APAF1
eClass 6.1	32160702
eClass 9.0	32160702
Available
Cross-Reactivity	Reacts with human, mouse, rat, cow, rabbit, hamster, guinea pig, and monkey.
Description	Rabbit Anti-Human APAF1 Affinity Purified polyclonal antibody. During apoptosis, APAF1 binds to cytochrome c (APAF2), a reaction that requires dATP, and this leads to the formation of a large multimeric complex. The complex recruits pro-caspase 9, and activates caspase 9 (APAF3). Activated caspase 9 in turn cleaves and activates caspase 3, one of the proteases responsible for the proteolytic cleavage of many key proteins in apoptosis. APAF1 is ubiquitously expressed in human tissues.
Formulation	Liquid in PBS, pH 7.2 + 30% glycerol + 0.05% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Immunogen	Synthetic peptide surrounding amino acid 1161 of human APAF1
Purification	Biospecific affinity chromatography
Storage and Stability	Store at -20C or in working aliquots at -80C for long term storage. Avoid repeated freeze-thaw cycles.
Specificity	Detects a 130 kDa protein corresponding to the apparent molecular weight of APAF1 on SDS-PAGE immunoblots.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

CS-CPA103.pdf

CS-CPA103-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ug

available

Delivery expected until 5/23/2024