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Rabbit Anti-Mouse MAPKAPK2 Affinity Purified pAb

Rabbit Anti-Mouse MAPKAPK2 Affinity Purified pAb

Manufacturer	Cell Sciences
Category	Oncology Antibodies By Cell Type Carcinoma Western Blot Primary Antibodies
Type	Antibody Polyclonal
Specific against	Mouse
Isotype	IgG
Applications	WB
Amount	100 ug
Host	Rabbit
Item no.	CS-CPM111
Targets	RPS6KC1
eClass 6.1	32160702
eClass 9.0	32160702
Available
Cross-Reactivity	Reacts with human, rat, dog, cow, and hamster.
Description	Rabbit Anti-Mouse MAPKAPK2 Affinity Purified polyclonal antibody. MAPKAPK2, also known as p45 hsp27 kinase, is a 45-54 kDa serine-threonine protein kinase that contains a proline rich sequence and two putative SH3-binding sites. MAPKAPK2 is activated in response to stress, IL1, and TNF, possibly catalyzed by p38/Hog-dependent phosphorylation. Hsp27 is one of the major substrates of MAPKAPK2, it stimulates actin polymerization in order to facilitate recovery from destruction of the cytoskeleton during cellular stresses. Two isoforms differing in their C-terminals are produced due to alternative splicing of the same gene. This antibody recognizes both isoforms.
Formulation	Liquid in PBS, pH 7.2 + 30% glycerol + 0.5% BSA + 0.01% thimerosal. Precaution: Thimerosal is a poisonous and hazardous substance which should be handled by trained staff only.
Immunogen	Synthetic peptide surrounding amino acid 365 of mouse MAPKAPK2
Purification	Biospecific affinity chromatography
Storage and Stability	Store at -20C or in working aliquots at -80C. Avoid repeated freeze-thaw cycles.
Specificity	Recognizes both 43 and 60 kDa isoforms, corresponding to the apparent molecular mass of MAPKAPK2 on SDS-PAGE immunoblots. These 43 kDa and 60 kDa bands can be specifically inhibited by the relevant peptide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

CS-CPM111.pdf

CS-CPM111-datasheet.pdf

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Amount: 100 ug

available

Delivery expected until 5/30/2024