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PC-3 cells

PC-3 cells

Item no.	C0019002
Manufacturer	Addexbio
Amount	One Frozen vial
Category	Oncology Neuroscience Neural Lineage Markers Metabolism Diabetes Glucose Homeostasis Neural Signaling Cell Lines & Cell Culture Cell Lines By Organ Bladder Cancer Testicular & Prostate Cancer
Type	Tumour Cells
Specific against	Human (Homo sapiens)
Dry ice	Yes
Citations	1.Vyas, H. K., Pal, R., Lohiya, N. K., and Talwar, G. P. A partner monoclonal antibody to Moab 730 kills 100% of DU145 and PC3 androgen-independent cancer cells. J Biosci, 34: 909-916, 2009. 2.Roca, H., Varsos, Z. S., and Pienta, K. J. CCL2 is a negative regulator of AMP-activated protein kinase to sustain mTOR complex-1 activation, survivin expression, and cell survival in human prostate cancer PC3 cells. Neoplasia, 11: 1309-1317, 2009. 3.Olea-Herrero, N., Vara, D., Malagarie-Cazenave, S., and Diaz-Laviada, I. The cannabinoid R+ methanandamide induces IL-6 secretion by prostate cancer PC3 cells. J Immunotoxicol, 6: 249-256, 2009. 4.Pei, Z., Li, H., Guo, Y., Jin, Y., and Lin, D. Sodium selenite inhibits the expression of VEGF, TGFbeta(1) and IL-6 induced by LPS in human PC3 cells via TLR4-NF-(K)B signaling blockage. Int Immunopharmacol, 10: 50-56. 5.Olea-Herrero, N., Vara, D., Malagarie-Cazenave, S., and Diaz-Laviada, I. The cannabinoid R(+)methanandamide induces IL-6 secretion by prostate cancer PC3 cells. J Immunotoxicol, 2009. 6.Chen, J., Xia, D., Luo, J. D., and Wang, P. Exogenous p27KIP1 expression induces anti-tumour effects and inhibits the EGFR/PI3K/Akt signalling pathway in PC3 cells. Asian J Androl, 11: 669-677, 2009. 7.Zhou, Q., Yan, B., Hu, X., Li, X. B., Zhang, J., and Fang, J. Luteolin inhibits invasion of prostate cancer PC3 cells through E-cadherin. Mol Cancer Ther, 8: 1684-1691, 2009.
ECLASS 10.1	32160890
ECLASS 11.0	32160890
UNSPSC	41106509
Available
Description	Disease: Prostatic adenocarcinoma grade IV Origin: Derived from metastatic bone Species: Homo sapiens Tissue: Prostate Morphology: Epithelial Properties: Adherent Cytogenic data: The line is near-triploid Patient: Male, Caucasian, 62 yrs of age Medium: RPMI1640 + 10% FBS Subculture: 1:3 to 1:6 using 0.25% trypsin or trypsin/EDTA, 5% CO2; 37C Freezing Medium: Complete culture medium supplemented with 5% (v/v) DMSO Biosafety Level: I Sterility: Bacteria: Negative Yeast: Negative Mycoplasma: Negative Pathogens: HIV: Negative Hepatitis B: Negative Hepatitis C: Negative Protein Expression: HLA A1, A9 DNA Profile (STR): Amelogenin: X CSF1PO: 11; D13S317: 11; D16S539: 11; D5S818: 13; D7S820: 8, 11; THO1: 6, 7; TPOX: 8, 9; vWA: 17 Mutations in PC-3 Cells Related cells by Organ: PC-3 cells VcaP cells
Storage condition	LN2
Manufacturer - Category	Cell Lines

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: One Frozen vial

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Delivery expected until 1/8/2026

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