TGS1 Antibody

TGS1

Cap specific guanine N2 methyltransferase antibody; Cap-specific guanine-N2 methyltransferase antibody; CLL associated antigen KW 2 antibody; CLL-associated antigen KW-2 antibody; DKFZp762A163 antibody; FLJ22995 antibody; HCA137 antibody; Hepatocellular carcinoma associated antigen 137 antibody; Hepatocellular carcinoma-associated antigen 137 antibody; NCOA6IP antibody; Nuclear receptor coactivator 6 interacting protein antibody; Nuclear receptor coactivator 6-interacting protein antibody; PIMT antibody; PIPMT antibody; PRIP interacting protein PIPMT antibody; PRIP interacting protein with methyltransferase domain antibody; PRIP interacting protein with methyltransferase motif antibody; PRIP-interacting protein with methyltransferase motif antibody; SEREX defined antibody; TGS 1 antibody; Tgs1 antibody; TGS1_HUMAN antibody; Trimethylguanosine synthase antibody; Trimethylguanosine synthase homolog (S. cerevisiae) antibody; Trimethylguanosine synthase homolog antibody

Recombinant Human Trimethylguanosine synthase protein (713-853AA)

Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m7G) caps of snRNAs and snoRNAs to a 2, 2, 7-trimethylguanosine (m(2, 2, 7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.

>95%, Protein G purified

Signal Transduction

Recombinant Human Trimethylguanosine synthase protein (713-853AA)