SLC25A33 Antibody

Polyclonal Antibody

SLC25A33

BMSC MCP antibody, BMSC-MCP antibody, Bone marrow stromal cell mitochondrial carrier protein antibody, HuBMSC MCP antibody, HuBMSC-MCP antibody, MGC4399 antibody, Mitochondrial carrier protein antibody, Novel mitochondrial carrier protein antibody, PNC1 protein antibody, Protein PNC1 antibody, S2533_HUMAN antibody, Slc25a33 antibody, Solute carrier family 25 member 33 antibody

Recombinant Human Solute carrier family 25 member 33 protein (66-120AA)

Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria (PubMed:25320081). Transports preferentially uracil, thymine, and cytosine (deoxy)nucleoside di- and triphosphates by an antiport mechanism (PubMed:25320081). Also transports guanine but not adenine (deoxy)nucleotides (PubMed:25320081). Is inhibited strongly by pyridoxal 5'-phosphate, 4, 7-diphenyl-1, 10-phenanthroline, tannic acid, and mercurials (mercury dichloride, mersalyl acid, p-hydroxymercuribenzoate) (PubMed:25320081). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration (PubMed:20453889). Upon INS or IGF1 stimulation regulates cell growth and proliferation by controlling mitochondrial DNA replication and transcription, the ratio of mitochondria-to nuclear-encoded components of the electron transport chain resulting in control of mitochondrial ROS production (PubMed:20453889, PubMed:17596519). Participates in dendritic cell endocytosis and may associate with mitochondrial oxidative phosphorylation (PubMed:14715278).

>95%, Protein G purified

Signal Transduction

Recombinant Human Solute carrier family 25 member 33 protein (66-120AA)