TDRD1 Antibody

TDRD1

Cancer/testis antigen 41.1 antibody; CT41.1 antibody; FLJ21082 antibody; MTR 1 antibody; TDRD 1 antibody; tdrd1 antibody; TDRD1_HUMAN antibody; Tudor domain containing 1 antibody; Tudor domain containing protein 1 antibody; Tudor domain-containing protein 1 antibody

Recombinant Human Tudor domain-containing protein 1 protein (12-314AA)

Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into Piwi proteins (By similarity).

>95%, Protein G purified

Developmental Biology

Recombinant Human Tudor domain-containing protein 1 protein (12-314AA)