UBE2T Antibody

Polyclonal Antibody

UBE2T

Cell proliferation inducing gene 50 protein antibody, Cell proliferation-inducing gene 50 protein antibody, HSPC150 antibody, HSPC150 protein similar to ubiquitin conjugating enzyme antibody, PIG50 antibody, Ube2t antibody, UBE2T_HUMAN antibody, Ubiquitin carrier protein T antibody, Ubiquitin conjugating enzyme antibody, ubiquitin conjugating enzyme E2 T antibody, Ubiquitin conjugating enzyme E2T antibody, Ubiquitin protein ligase T antibody, Ubiquitin-conjugating enzyme E2 T antibody, Ubiquitin-protein ligase T antibody

Recombinant Human Ubiquitin-conjugating enzyme E2 T protein (1-197AA)

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair: acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination.

>95%, Protein G purified

Cell Biology

Recombinant Human Ubiquitin-conjugating enzyme E2 T protein (1-197AA)