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RBL1 Antibody

RBL1 Antibody

Item no.	CSB-PA019398LA01HU-50ug
Manufacturer	Cusabio
Amount	50 ug
Quantity options	100 ug 20 ug 50 ug
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Cell Status Western Blot ELISA Immunofluorescence Senescence Primary Antibodies Astrocytoma By Organ Bladder Cancer Immunostaining Bone Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	107 kDa retinoblastoma-associated protein antibody,Cellular protein 107 antibody,Cellular protein p107 antibody,CP107 antibody,MGC40006 antibody,p107 antibody,PRB1 antibody,RBL1 antibody,RBL1_HUMAN antibody,Retinoblastoma like protein 1 antibody,retinoblastoma-like 1 (p107) antibody,Retinoblastoma-like protein 1 antibody
Similar products	RBL1, Retinoblastoma-like protein 1 (107 kDa retinoblastoma-associated protein) (p107) (pRb1)
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	ELISA, WB; Recommended dilution: WB:1:2000-1:5000
Manufacturer - Targets	RBL1
Storage Conditions	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Manufacturer - Alias	107 kDa retinoblastoma-associated protein antibody, Cellular protein 107 antibody, Cellular protein p107 antibody, CP107 antibody, MGC40006 antibody, p107 antibody, PRB1 antibody, RBL1 antibody, RBL1_HUMAN antibody, Retinoblastoma like protein 1 antibody, retinoblastoma-like 1 (p107) antibody, Retinoblastoma-like protein 1 antibody
Immunogen Species	Human
Immunogen	Recombinant Human Retinoblastoma-like protein 1 protein (201-500AA)
Dilution	ELISA:1:2000-1:10000 WB:1:2000-1:5000
Background	Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation. Forms a complex with adenovirus E1A and with SV40 large T antigen. May bind and modulate functionally certain cellular proteins with which T and E1A compete for pocket binding. May act as a tumor suppressor.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method	>95%, Protein G purified
General Research Areas	Cell Biology
Initial Research Areas	Cell Biology
Antigen Species	Human
Antigen	Recombinant Human Retinoblastoma-like protein 1 protein (201-500AA)
Clonality	Polyclonal

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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Delivery expected until 12/4/2025

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