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Recombinant Human Plasminogen activator inhibitor 2 protein(SERPINB2) (Active)

Recombinant Human Plasminogen activator inhibitor 2 protein(SERPINB2) (Active)

Item no.	CSB-AP000151HU-1
Manufacturer	Cusabio
Amount	1 mg
Quantity options	1 mg 10 ug 100 ug 2 ug 250 ug 500 ug
Category	Oncology Food Safety Proteins Peptides & Proteins Recombinant Proteins By Organ Breast Cancer
Type	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Purity	>95% as determined by SDS-PAGE and HPLC.
Sequence	MEDLCVANTL FALNLFKHLA KASPTQNLFL SP WSISSTMA MVYMGSRGST EDQMAKVLQF NEVG ANAVTP MTPENFTSCG FMQQIQKGSY PDAILQ AQAA DKIHSSFRSL SSAINASTGN YLLESVNK LF GEKSASFREE YIRLCQKYYS SEPQAVDFLE CAEEARKKIN SWVKTQTKGK IPNLLPEGSV D GDTRMVLVN AVYFKGKWKT PFEKKLNGLY PFR VNS
Protein Family	Serpin family, Ov-serpin subfamily
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	PAI-2,Placental plasminogen activator inhibitor,Serpin B2,Urokinase inhibitor,
Available
Manufacturer - Category	Enzyme / Enzyme
Manufacturer - Conjugate / Tag	Tag-Free
Molecular Weight	46.6 kDa
Buffer	0.2 um filtered 20 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1 mM Cysteine, with 5 % Trehalose , lyophilized
General Research Areas	Immunology
Relevance	Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
Expression Region	1-415aa
Function	Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.
Subcellular Location	Cytoplasm, Secreted, extracellular space
Pathway	Complementandcoagulationcascades
Gene Names	SERPINB2, PAI2, PLANH2
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Biological activity	Fully biologically active when compared to standard. The biologically active was determined by its inhibitory effect against single chain tPA induced cleavage of a chromogenic substrate in Imidazole Buffer at 37 C. Half maximal inhibition against 1.0 ug/ml of single chain tPA was at a concentration of 1.0 ug/ml.
Manufacturer - Format	Lyophilized powder
Uniprot Entry Name	PAI2_HUMAN
Protein Description	Full Length
PubMed ID	3029122; 3325828; 3496414; 3257578; 2494165; 2303256; 15489334; 1286667; 14732874; 21269460; 10368272; 10391209

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mg

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Delivery expected until 10/30/2025

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