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Recombinant Human Interleukin-20 protein(IL20) (Active)

Recombinant Human Interleukin-20 protein(IL20) (Active)

Item no.	CSB-AP001871HU-1
Manufacturer	Cusabio
Amount	1 mg
Quantity options	1 mg 10 ug 100 ug 2 ug 250 ug 500 ug
Category	Neuroscience Neural Lineage Markers Neural Transcription Factors Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Conjugate/Tag	Tag Free
Purity	>95% as determined by SDS-PAGE and HPLC.
Sequence	M+LKTLNLGSC VIATNLQEIR NGFSEIRGSV Q AKDGNIDIR ILRRTESLQD TKPANRCCLL RHL LRLYLDR VFKNYQTPDH YTLRKISSLA NSFLT IKKDL RLCHAHMTCH CGEEAMKKYS QILSHFE KLE PQAAVVKALG ELDILLQWME ETE
Protein Family	IL-10 family
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IL-20,
Available
Manufacturer - Category	Cytokine / Interleukin
Molecular Weight	17.6 kDa
Buffer	0.2 um filtered PBS, pH 7.2, with trehalose , lyophilized
General Research Areas	Immunology
Relevance	Proinflammatory and angiogenic cytokine that may be involved in epidermal function and psoriasis. Angiogenic and proliferative activities are antagonized by IL10. May act through STAT3. {ECO:0000269\|PubMed:16511554}.
Expression Region	25-176aa
Function	Proinflammatory and angiogenic cytokine that may be involved in epidermal function and psoriasis. Angiogenic and proliferative activities are antagonized by IL10. May act through STAT3.
Subcellular Location	Secreted
Tissue Specificity	Expressed in most tissues and five major cell types: epithelial cells (primarily skin, buccal mucosa, tongue, nasal mucosa, lung, ureter, breast, prostate, fallopian tube, and adrenal gland), myoepithelial cells (mainly prostate), endothelial cells (mainly in small vessels or capillaries), macrophages, and skeletal muscle. Isoform 2 was detected in the lung tissue only.
Pathway	Jak-STATsignalingpathway
Gene Names	IL20, ZCYTO10, UNQ852/PRO1801
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Biological activity	Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human IL-20Ralpha and human IL-20Rbeta co-transfected murine BaF3 pro-B cells is less than 0.5 ng/ml, corresponding to a specific activity of ? 2.0 x106 IU/mg.
Manufacturer - Format	Lyophilized powder
Uniprot Entry Name	IL20_HUMAN
Protein Description	Full Length of Mature Protein
PubMed ID	11163236; 16511554; 12975309; 16710414; 15489334; 15340161; 16908179; 16709143; 22802649

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1 mg

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Delivery expected until 12/18/2025

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