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Recombinant Mouse Lymphotactin protein(Xcl1) (Active)

Recombinant Mouse Lymphotactin protein(Xcl1) (Active)

Manufacturer	Cusabio
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	Mouse
Format	Lyophilized powder
Amount	100ug
Item no.	CSB-AP001201MO-100
eClass 6.1	34160400
eClass 9.0	42020190
Available
Classification	Cytokine
Subdivision	Chemokine
Research Areas	Immunology
Uniprot NO.	P47993
Uniprot Entry Name	XCL1_MOUSE
Gene Names	Xcl1, Lptn, Ltn, Scyc1
Source	E.Coli
Expression Region	22-114aa
Sequence	VGTEVLEESS CVNLQTQRLP VQKIKTYIIW EG AMRAVIFV TKRGLKICAD PEAKWVKAAI KTVD GRASTR KNMAETVPTG AQRSTSTAIT LTG
Protein Description	Full Length of Mature Protein
Tag Info	Tag-Free
Mol. Weight	10.1 kDa
Biological Activity	Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human XCR1 transfected murine BaF3 cells is less than 100 ng/ml, corresponding to a specific activity of ? 1.0 x104 IU/mg.
Purity	>97% as determined by SDS-PAGE and HPLC.
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer	0.2 um filtered PBS, pH 7.4 , lyophilized
Alias	C motif chemokine 1, Lymphotaxin, Small-inducible cytokine C1
Relevance	Chemotactic activity for lymphocytes but not for monocytes or neutrophils.
PubMed ID	7973732; 7875320; 9199871; 15489334
Function	Chemotactic activity for lymphocytes but not for monocytes or neutrophils. In thymus, mediates medullary accumulation of thymic dendritic cells and contributes to regulatoy T cell development, playing a role in self-tolerance establishment.
Subcellular Location	Secreted
Protein Families	Intercrine gamma family
Tissue Specificity	Expressed in activated CD8(+) T cells. In the thymus, expressed by medullary thymic epithelial cells.
Tag Information	Tag-Free

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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