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Recombinant Human C-C motif chemokine 15 protein(CCL15) (Active)

Recombinant Human C-C motif chemokine 15 protein(CCL15) (Active)

Item no.	CSB-AP000581HU-100
Manufacturer	Cusabio
Amount	100 ug
Quantity options	1 mg 100 ug 25 ug 250 ug 5 ug 500 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Lyophilized powder
Specific against	other
Host	E.coli
Purity	>98% as determined by SDS-PAGE and HPLC.
Sequence	SFHFAADCCT SYISQSIPCS LMKSYFETSS EC SKPGVIFL TKKGRQVCAK PSGPGVQDCM KKLK PYSI
Protein Family	Intercrine beta (chemokine CC) family
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Chemokine CC-2, Leukotactin-1, LKN-1, MIP-1 delta, Macrophage inflammatory protein 5
Available
Manufacturer - Category	Cytokine / Chemokine
Manufacturer - Conjugate / Tag	Tag-Free
Molecular Weight	7.4 kDa
General Research Areas	Immunology
Relevance	Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15. {ECO:0000269\|PubMed:15905581}.
Function	Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15.
Subcellular Location	Secreted
Tissue Specificity	Most abundant in heart, skeletal muscle and adrenal gland. Lower levels in placenta, liver, pancreas and bone marrow. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are found in high levels in synovial fluids from rheumatoid patients.
Paythway	Chemokinesignalingpathway
Gene Names	CCL15, MIP5, NCC3, SCYA15
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer	0.2 um filtered PBS, pH 7.4 , lyophilized
Uniprot Entry Name	CCL15_HUMAN
Expression Region	46-113aa
Protein Description	Partial
Biological Activity	Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10 ng/ml.
PubMed ID	9548457; 9624581; 9600961; 10213461; 15489334; 15340161; 9129202; 9558365; 15905581; 10320325

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 9/11/2025

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