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Recombinant Human Interleukin-15 protein(IL15) (Active)

Recombinant Human Interleukin-15 protein(IL15) (Active)

Manufacturer	Cusabio
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Format	Lyophilized powder
Amount	100ug
Host	E.coli
Item no.	CSB-AP001621HU-100
eClass 6.1	34160400
eClass 9.0	42020190
Available
Classification	Cytokine
Subdivision	Interleukin
Research Areas	Immunology
Uniprot NO.	P40933
Uniprot Entry Name	IL15_HUMAN
Gene Names	IL15
Source	E.Coli
Expression Region	49-162aa
Sequence	NWVNVISDLK KIEDLIQSMH IDATLYTESD VH PSCKVTAM KCFLLELQVI SLESGDASIH DTVE NLIILA NNSLSSNGNV TESGCKECEE LEEKNI KEFL QSFVHIVQMF INTS
Protein Description	Full Length of Mature Protein
Tag Info	Tag-Free
Mol. Weight	12.9 kDa
Biological Activity	Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.5 ng/ml, corresponding to a specific activity of ? 2.0 x 106 IU/mg.
Purity	>97% as determined by SDS-PAGE and HPLC.
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer	0.2 um filtered PBS, pH 7.4, lyophilized
Alias	IL-15,
Relevance	Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha.
PubMed ID	8178155; 8932977; 8668345; 9405632; 14702039; 15489334; 21167836
Function	Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha.
Subcellular Location	Isoform IL15-S48AA: Secreted, SUBCELLULAR LOCATION: Isoform IL15-S21AA: Cytoplasm, Nucleus
Protein Families	IL-15/IL-21 family
Tissue Specificity	Most abundant in placenta and skeletal muscle. It is also detected in the heart, lung, liver and kidney. IL15-S21AA is preferentially expressed in tissues such as testis and thymus.
Paythway	Jak-STATsignalingpathway
Tag Information	Tag-Free

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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