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Recombinant Human Interleukin-17A protein(IL17A) (Active)

Recombinant Human Interleukin-17A protein(IL17A) (Active)

Item no.	CSB-AP001851HU-100
Manufacturer	Cusabio
Amount	100 ug
Quantity options	1 mg 100 ug 25 ug 250 ug 5 ug 500 ug
Category	Metabolism Diabetes Glucose Homeostasis Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Lyophilized powder
Specific against	other
Host	E.coli
Purity	>95% as determined by SDS-PAGE and HPLC.
Sequence	GITIPRNPGC PNSEDKNFPR TVMVNLNIHN RN TNTNPKRS SDYYNRSTSP WNLHRNEDPE RYPS VIWEAK CRHLGCINAD GNVDYHMNSV PIQQEI LVLR REPPHCPNSF RLEKILVSVG CTCVTPIV HH VA
Protein Family	IL-17 family
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IL-17, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8
Available
Manufacturer - Category	Cytokine / Interleukin
Manufacturer - Conjugate / Tag	Tag-Free
Molecular Weight	31.0 kDa
General Research Areas	Immunology
Relevance	Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.
Function	Ligand for IL17RA and IL17RC
Subcellular Location	Secreted
Tissue Specificity	Restricted to activated memory T-cells.
Paythway	IL-17signalingpathway
Gene Names	IL17A, CTLA8, IL17
Endotoxin	Less than 1.0 EU/ug as determined by LAL method.
Storage Buffer	0.2 um filtered PBS, pH 7.4 , lyophilized
Uniprot Entry Name	IL17_HUMAN
Expression Region	24-155aa
Protein Description	Full Length of Mature Protein
Biological Activity	Fully biologically active when compared to standard. The ED50 as determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 7.5 ng/ml, corresponding to a specific activity of ? 1.3 x 105 IU/mg.
PubMed ID	8676080; 7499828; 14574404; 15489334; 15340161; 19835883

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 10/2/2025

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