Manufacturer |
Cusabio
|
Category |
|
Type |
Proteins Recombinant |
Specific against |
other |
Format |
Liquid or Lyophilized powder |
Amount |
10ug |
Host |
E.coli |
Item no. |
CSB-EP011670MO-10 |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Available |
|
Research Topic |
Immunology |
Uniprot ID |
P16872 |
Gene Names |
Il7r |
Organism |
Mus musculus (Mouse) |
AA Sequence |
ESGNAQDGDLEDADADDHSFWCHSQLEVDGSQHLL TCAFNDSDINTANLEFQICGALLRVKCLTLNKLQD IYFIKTSEFLLIGSSNICVKLGQKNLTCKNMAINT IVKAEAPSDLKVVYRKEANDFLVTFNAPHLKKKYL KKVKHDVAYRPARGESNWTHVSLFHTRTTIPQRKL RPKAMYEIKVRSIPHNDYFKGFWSEWSPSSTFETP EPKNQGGWD |
Expression Region |
21-239aa |
Sequence Info |
Extracellular Domain |
Source |
E.coli |
Tag Info |
N-terminal 6xHis-SUMO-tagged |
MW |
41 kDa |
Alternative Name(s) |
Short name: IL-7 receptor subunit alpha Short name: IL-7R subunit alpha Short name: IL-7R-alpha Short name: IL-7RA |
Relevance |
Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). |
Reference |
"Structural basis of the proinflammatory signaling complex mediated by TSLP."Verstraete K., van Schie L., Vyncke L., Bloch Y., Tavernier J., Pauwels E., Peelman F., Savvides S.N.Nat. Struct. Mol. Biol. 21:375-382(2014) |
Purity |
Greater than 90% as determined by SDS-PAGE. |
Storage Buffer |
Tris-based buffer, 50% glycerol |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). |
Subcellular Location |
Membrane, Single-pass type I membrane protein |
Protein Families |
Type I cytokine receptor family, Type 4 subfamily |
Tissue Specificity |
Spleen, thymus and fetal liver. |
Tag Information |
N-terminal 6xHis-SUMO-tagged |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.