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Recombinant Human Macrophage mannose receptor 1(MRC1),partial

Recombinant Human Macrophage mannose receptor 1(MRC1),partial

Manufacturer	Cusabio
Category	Neuroscience Neural Lineage Markers Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	other
Format	Liquid or Lyophilized powder
Amount	10ug
Host	E.coli
Item no.	CSB-EP014783HU-10
eClass 6.1	34160400
eClass 9.0	42020190
Available
Research Topic	Immunology
Uniprot ID	P22897
Gene Names	MRC1
Organism	Homo sapiens (Human)
AA Sequence	RTSLCFKLYAKGKHEKKTWFESRDFCRALGGDLAS INNKEEQQTIWRLITASGSYHKLFWLGLTYGSPSE GFTWSDGSPVSYENWAYGEPNNYQNVEYCGELKGD PTMSWNDINCEHLNNWICQIQKGQTPKPEPTPAPQ DNPPVTEDGWVIYKDYQYYFSKEKETMDNARAFCK RNFGDLVSIQSESEKKFLWKYVNRNDAQSAYFIGL LISLDKKFAWMDGSKVDYVSWATGEPNFANEDENC VTMYSNSGFWNDINCGYPNAFICQRHNSSINATTV MPTMPSVPSGCKEGWNFYSNKCFKIFGFMEEERKN WQEARKACIGFGGNLVSIQNEKEQAFLTYHMKDST FSAWTGLNDVNSEHTFLWTDGRGVHYTNWGKGYPG GRRSSLSYEDADCVVIIGGASNEAGKWMDDTCDSK RGYICQTRSDPSLTNPPATIQTDGFVKYGKSSYSL MRQKFQWHEAETYCKLHNSLIASILDPYSNAFAWL QMETSNERVWIALNSNLTDNQYTWTDKWRVRYTNW AADEPKLKSACVYLDLDGYWKTAHCNESFYFLCK
Expression Region	655-1213aa
Sequence Info	Partial
Source	E.coli
Tag Info	N-terminal 6xHis-SUMO-tagged
MW	80.4 kDa
Alternative Name(s)	C-type lectin domain family 13 member DC-type lectin domain family 13 member D-like; Macrophage mannose receptor 1-like protein 1; CD206
Relevance	Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.
Reference	An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.J. Proteomics 96:253-262(2014)
Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	Tris-based buffer, 50% glycerol
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.; FUNCTION
Subcellular Location	Endosome membrane, Single-pass type I membrane protein, Cell membrane, Single-pass type I membrane protein
Tag Information	N-terminal 6xHis-SUMO-tagged

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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