Comparison

Recombinant Escherichia coli Ribonucleoside-diphosphate reductase 1 subunit alpha(nrdA)

Item no. CSB-EP355522ENV-10
Manufacturer Cusabio
Amount 10 ug
Quantity options 1 mg 10 ug 100 ug 20 ug 200 ug 50 ug 500 ug
Category
Type Proteins Recombinant
Format Liquid or Lyophilized powder
Specific against other
Host E.coli
Conjugate/Tag SUMO, HIS
Purity Greater than 90% as determined by SDS-PAGE.
Sequence MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHN VSISQVELRSHIQFYDGIKTSDIHETIIKAAADLI SRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDH VVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRD MTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYIL VAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTP IMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIV KYV
Protein Family Ribonucleoside diphosphate reductase large chain family
Citations Two conserved tyrosine residues in protein R1 participate in an intermolecular electron transfer in ribonucleotide reductase.Ekberg M., Sahlin M., Eriksson M., Sjoberg B.M.J. Biol. Chem. 271:20655-20659(1996)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Protein B1Ribonucleoside-diphosphate reductase 1 R1 subunitRibonucleotide reductase 1
Available
Manufacturer - Conjugate / Tag
N-terminal 6xHis-SUMO-tagged
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Molecular Weight
101.8 kDa
Relevance
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines.
Expression Region
1-761aa
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines.
Gene Names
nrdA
Sequence Info
Full Length
Organism
Escherichia coli (strain K12)
Storage Buffer
Tris-based buffer, 50% glycerol

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10 ug
Available: In stock
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