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Recombinant Human Retinal dehydrogenase 2(ALDH1A2)

Recombinant Human Retinal dehydrogenase 2(ALDH1A2)

Manufacturer	Cusabio
Category	Oncology Peptides & Proteins Recombinant Proteins By Organ Heart & Blood Cancer
Type	Proteins Recombinant
Specific against	other
Format	Liquid or Lyophilized powder
Amount	10ug
Host	Yeast
Item no.	CSB-YP001566HU-10
eClass 6.1	34160400
eClass 9.0	42020190
Available
Research areas	Neuroscience
Target / Protein	ALDH1A2
Biologically active	Not Test
Expression system	Yeast
Species of origin	Homo sapiens (Human)
Uniprot ID	O94788
AA Sequence	MTSSKIEMPGEVKADPAALMASLHLLPSPTPNLEI KYTKIFINNEWQNSESGRVFPVYNPATGEQVCEVQ EADKADIDKAVQAARLAFSLGSVWRRMDASERGRL LDKLADLVERDRAVLATMESLNGGKPFLQAFYVDL QGVIKTFRYYAGWADKIHGMTIPVDGDYFTFTRHE PIGVCGQIIPWNFPLLMFAWKIAPALCCGNTVVIK PAEQTPLSALYMGALIKEAGFPPGVINILPGYGPT AGAAIASHIGIDKIAFTGSTEVGKLIQEAAGRSNL KRVTLELGGKSPNIIFADADLDYAVEQAHQGVFFN QGQCCTAGSRIFVEESIYEEFVRRSVERAKRRVVG SPFDPTTEQGPQIDKKQYNKILELIQSGVAEGAKL ECGGKGLGRKGFFIEPTVFSNVTDDMRIAKEEIFG PVQEILRFKTMDEVIERANNSDFGLVAAVFTNDIN KALTVSSAMQAGTVWINCYNALNAQSPFGGFKMSG NGREMGEFGLREYSEVKTVTVKIPQKNS
Tag Info	N-terminal 6xHis-tagged
Expression Region	1-518aa
Protein length	Full Length
MW	58.7 kDa
Alternative Name(s)	Aldehyde dehydrogenase family 1 member A2 Retinaldehyde-specific dehydrogenase type 2 Short name: RALDH(II)
Relevance	Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently
References	"TAL1 and LIM-only proteins synergistically induce retinaldehyde dehydrogenase 2 expression in T-cell acute lymphoblastic leukemia by acting as cofactors for GATA3."Ono Y., Fukuhara N., Yoshie O.Mol. Cell. Biol. 18:6939-6950(1998)
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Does metabolize octanal and decanal but does not metabolize citral, benzaldehyde, acetaldehyde and propanal efficiently (By similarity).
Subcellular Location	Cytoplasm
Protein Families	Aldehyde dehydrogenase family
Tag Information	N-terminal 6xHis-tagged

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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