DNMT3A Polyclonal Antibody

DNMT3A

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.

PBS with 0.05% sodium azide and 50% glycerol, PH7.4

IHC 1:100-1:300

DNMT3A

Recombinant protein of human DNMT3A