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MCM6 Polyclonal Antibody

MCM6 Polyclonal Antibody

Item no.	E-AB-14210-120
Manufacturer	Elabscience
Amount	120 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Neuroscience Neural Lineage Markers Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot ELISA Proliferation Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DNA replication licensing factor MCM6, MCG40308, Mcm6, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe), MCM6 minichromosome maintenance deficient 6, MCM6, Minichromosome maintenance complex component 6, Minichromosome maintenance deficient (mis5 S. pombe) 6, Minichromosome maintenance deficient 6 homolog, Minichromosome maintenance protein 6, Mis5, MIS5 homolog, p105MCM
Similar products	MCM6, DNA replication licensing factor MCM6, p105MCM, Mcm6, MCG40308, Mis5, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe), MIS5 homolog, MCM6 minichromosome maintenance deficient 6, Minichromosome maintenance complex component 6, Minichromosome maintenance deficient (mis5 S. pombe) 6, Minichromosome maintenance deficient 6 homolog, Minichromosome maintenance protein 6
Shipping condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	MCM6
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	93kDa
Research Areas	Cancer, Epigenetics and Nuclear Signaling
Background	The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication.
Concentration	0.8 mg/mL
Buffer	PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method	Affinity purification
Recommended Dilution	WB 1:500-1:2000; IHC 1:100-1:300
Santa Cruz #	sc-9843, sc-9845, sc-22781
Abbreviation	MCM6
Clonality	Polyclonal
Immunogen	Recombinant protein of human MCM6
Category ID III	Polyclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 120 uL

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Delivery expected until 7/10/2025

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