Item no. |
E-AB-14210-20 |
Manufacturer |
Elabscience
|
Amount |
20 uL |
Quantity options |
120 uL
20 uL
200 uL
60 uL
|
Category |
|
Type |
Antibody Polyclonal |
Applications |
WB, IHC |
Specific against |
Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus) |
Host |
Rabbit |
Isotype |
IgG |
Conjugate/Tag |
Unconjugated |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
DNA replication licensing factor MCM6, MCG40308, Mcm6, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe), MCM6 minichromosome maintenance deficient 6, MCM6, Minichromosome maintenance complex component 6, Minichromosome maintenance deficient (mis5 S. pombe) 6, Minichromosome maintenance deficient 6 homolog, Minichromosome maintenance protein 6, Mis5, MIS5 homolog, p105MCM |
Similar products |
MCM6, DNA replication licensing factor MCM6, p105MCM, Mcm6, MCG40308, Mis5, MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe), MIS5 homolog, MCM6 minichromosome maintenance deficient 6, Minichromosome maintenance complex component 6, Minichromosome maintenance deficient (mis5 S. pombe) 6, Minichromosome maintenance deficient 6 homolog, Minichromosome maintenance protein 6 |
Shipping condition |
Cool pack |
Hazard information |
Comply with cargo safety certificate |
Available |
|
Manufacturer - Category |
Primary Antibodies |
Manufacturer - Targets |
MCM6 |
Shipping Temperature |
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Storage Conditions |
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Calculated Molecular Weight |
93kDa |
Research Areas |
Cancer, Epigenetics and Nuclear Signaling |
Background |
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. |
Concentration |
0.8 mg/mL |
Buffer |
PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
Purification Method |
Affinity purification |
Recommended Dilution |
WB 1:500-1:2000; IHC 1:100-1:300 |
Santa Cruz # |
sc-9843, sc-9845, sc-22781 |
Abbreviation |
MCM6 |
Clonality |
Polyclonal |
Immunogen |
Recombinant protein of human MCM6 |
Category ID III |
Polyclonal Antibodies |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.