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CASP9 Monoclonal Antibody

CASP9 Monoclonal Antibody

Item no.	E-AB-22035-20
Manufacturer	Elabscience
Amount	20 uL
Quantity options	120 uL 20 uL 200 uL 60 uL
Category	Oncology Neuroscience Neural Signaling Neural Epigenetics Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Immunoprecipitation Western Blot Immunofluorescence Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies By Organ Colorectal Cancer Testicular & Prostate Cancer Gastric Cancer Uterine, Ovarian & Cervical Cancer
Type	Antibody Monoclonal
Applications	WB, IF, IP, IHC-P
Clone	3I3
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	https://pubs.rsc.org/en/content/articlelanding/2021/fo/d1fo01547h
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	APAF-3, APAF3, Apoptosis related cysteine peptidase, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, CASP-9, CASP9, CASP9, Caspase 9 apoptosis related cysteine peptidase, Caspase 9 Dominant Negative, Caspase 9c, Caspase-9, Caspase-9 subunit p10, ICE LAP6, ICE like apoptotic protease 6, ICE-LAP6, ICE-like apoptotic protease 6, MCH6, PPP1R56, protein phosphatase 1, regulatory subunit 56, RNCASP9
Similar products	Caspase-9, CASP9, MCH6, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, Caspase-9 subunit p10, protein phosphatase 1, APAF-3, APAF3, ICE-LAP6, Apoptosis related cysteine peptidase, PPP1R56, CASP-9, Caspase 9c, ICE LAP6, ICE like apoptotic protease 6, RNCASP9, Caspase 9 Dominant Negative, Caspase 9 apoptosis related cysteine peptidase, regulatory subunit 56
Shipping Condition	Cool pack
Hazard information	Comply with cargo safety certificate
Available
Manufacturer - Category	Primary Antibodies
Manufacturer - Targets	Caspase 9
Shipping Temperature	The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions	Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight	46kDa
Observed Molecular Weight	47-51kDa
Manufacturer - Research Areas	Cancer, Cell Biology, Metabolism
Background	Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Concentration	1 mg/mL
Buffer	PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification Method	Protein A purification
Recommended Dilution	WB 1:500-1:2000; IHC 1:50-300; IF 1:50-1:200; IP 1:100-1:300
Abbreviation	Caspase 9
Clonality	Monoclonal
Immunogen	Synthetic Peptide
Category ID III	Monoclonal Antibodies

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.