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BNIP3L ELISA Kit (Human) (OKCA01121)

BNIP3L ELISA Kit (Human) (OKCA01121)

Manufacturer	AVIVA Systems Biology
Category	Cell Biology Cell Status ELISA Autophagy ELISA & Immunoassays ELISA Kits Immunoassay
Type	Elisa-Kit
Specific against	other
Amount	96 Wells
Item no.	OKCA01121
eClass 6.1	32160605
eClass 9.0	32160605
Available
Gene symbol	BNIP3L
Protein name	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
Gene id	665
Reconstitution and storage	Store as indicated in product manual.
Description of target	Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
Assay info	Assay Methodology: Quantitative Sanadwich ELISA
Sensitivity	0.078 ng/mL
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 96 Wells

available

Delivery expected until 6/13/2024