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AFP Antibody

AFP Antibody

Item no.	E19-6007
Manufacturer	Enogene
Amount	100 ug/100 ul
Quantity options	100 ug/100 ul 100 ug/100 ul 50 ug/50 ul 100 ug/100 ul 100 ug/100 ul 100 ug/200 ul 100 ul 100 ul 100 ul 100 ul 100 ul 100 ul 100 ul 100 ul 100 ul 100 ul 200 ul 200 ul 200 ul 200 ul 100 ul 50 ul 100 ug 100 ul 100 ul
Category	Oncology Neuroscience Targets for Rodent Neurosciences Antibodies By Cell Type Carcinoma Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies By Organ Lung Cancer Hepatic Cancer
Type	Antibody
Applications	WB, IF, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	AFP , FETA, Alpha fetoglobulin, alpha fetoprotein, Alpha 1 fetoprotein, HPAFP
Available
Specificity	AFP Antibody detects endogenous levels of total AFP
Manufacturer - Applications	WB 1:500-1:2000 IHC 1:50-1:200 IF 1:10-1:100
Manufacturer - Conjugate / Tag	This antibody is also available with the following conjugates: AF350, AF405L, AF405M, AF405S, AF488, AF514, AF532, AF546, AF555, AF568, AF594, AF610, AF635, AF647, AF680, AF700, AF750, AF790, APC, AP, Biotin, Cy3, Cy5.5, Cy5, Cy7, FITC, HRP, PE, Magnetic beads (1 um, 2.8 um, 3 um, 4.5 um, 5 um, 10 um, 15 um, 20 um, 30 um, or different size option) Please contact sales@hoelzel.de for pricing and availability.
Storage Conditions	Store at -20C/1 year
Molecular Weight	65kDa
Immunogen	C term -peptideof human AFP
Purification	Immunogen affinity purified
Background	Alpha-fetoprotein (AFP) is a 65 kDa glycoprotein found in the serum of the mammalian fetal liver, yolk sac, and GI tract. While AFP expression in adult cells is low, it is aberrantly expressed in adult liver cancer cells (1, 2). The tumor suppressor gene p53 and beta-catenin are both involved in the regulation of AFP expression. In normal adult cells, p53 binds to the repressor region of the AFP gene, thereby blocking transcription. Mutations in both p53 and beta-catenin are associated with aberrant expression of AFP. Elevated serum levels are predictive of hepatocellular carcinoma (3).
Formulation Description	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 C.Stable for 12 months from date of receipt
CiteID	EN0042731

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug/100 ul

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Delivery expected until 9/25/2025

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