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Human FcRn / FCGRT&B2M Heterodimer Protein, His Tag (SPR & BLI verified)

Human FcRn / FCGRT&B2M Heterodimer Protein, His Tag (SPR & BLI verified)

Manufacturer	ACROBiosystems
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	Human
Format	Powder
Amount	1mg
Item no.	FCN-H52W7-1mg
Conjugate/Tag	His
eClass 6.1	34160400
eClass 9.0	42020190
Available
Buffer	PBS, pH7.4
Characteristics	Human FCGRT&B2M Heterodimer Protein, His Tag (SPR & BLI verified), produced by co-expression of FCGRT and B2M, has a calculated MW of 32.3 kDa (FCGRT) and 11.7 kDa (B2M). Subunit FCGRT is fused with a polyhistidine tag at the C-terminus and subunit Beta-2
Description	FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51 (equivalent to FCGRT), and p14 (equivalent to beta-2-microglobulin), and forms an MHC class I-like heterodimer. Fc fragment of IgG, receptor, transporter, alpha (FCGRT) binds to the Fc region of monomeric immunoglobulins gamma and mediates the uptake of IgG from milk. FCGRT possible role in transfer of immunoglobulin G from mother to fetus. Beta-2-microglobulin (B2M) is a component of the class I major histocompatibility complex (MHC) and involved in the presentation of peptide antigens to the immune system.
Endotoxin Level	Less than 1.0 EU per ug by the LAL method.
Exp Region	Ala 24 - Ser 297 (FCGRT) & Ile 21 - Met 119 (B2M)
Expression System	HEK293
Molecular Weight	32.3 kDa (FCGRT) & 11.7 kDa (B2M)
Molecule	FcRn (FCGRT & B2M)
Shipping Conditions	RT
Storage	-20C

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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Amount: 1mg

available

Delivery expected until 6/6/2024