PTH (1-84aa), Human

Parathyroid Hormone (PTH), is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. Parathyroid Hormone (PTH) is secreted from cells of the parathyroid glands and finds Parathyroid Hormone's major target cells in bone and kidney. Like most other protein hormones, Parathyroid Hormone (PTH) is synthesized as a preprohormone. After intracellular processing, the mature hormone is packaged within the Golgi into secretory vesicles, the secreted into blood by exocytosis. Parathyroid Hormone (PTH) is secreted as a linear protein of 84 amino acids. Recombinant, Human Parathyroid Hormone (PTH), produced in, E. coli, is a single, non-glycosylated, polypeptide chain containing 84 amino acids and having a molecular mass of 9, 000 Da.

The protein (1 mg/ml) was lyophilized after extensive dialyses against 1.15 mg sodium citrate, sodium chloride 7.31 mg, 0.21 mg citric acid, 0.1117 mg EDTA-Na2, 0.2 mg Tween 80 and 50 mg Mannitol.

Cytokine, Chemokines & Growth Factors

Lyophilized, Human Parathyroid Hormone (PTH ), remains stable at room temperature for three weeks, but it is best stored desiccated below -18C. Upon reconstitution Human Parathyroid Hormone (PTH )should be stored at 4C for up to seven days. For long term storage it is recommended that a carrier protein (0.1% HSA or BSA ) be added. Avoid repeated freeze-thaw cycles.

Hormones