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MIP-1 alpha/CCL3, Human

MIP-1 alpha/CCL3, Human

Manufacturer	GenScript
Category	Peptides & Proteins Recombinant Proteins Cell Biology Cell Status Apoptosis
Type	Proteins
Specific against	Human
Amount	10ug
Item no.	Z03131-10
Targets	TNFSF12
eClass 6.1	34160400
eClass 9.0	42020190
Available
Description	MIP-1 alpha/CCL3, also known as LD78 alpha, is an inflammatory chemokine. MIP-1alpha belongs to the CCL chemokine family, and shares 68% homology with MIP-1beta. The mature form of MIP-1alpha contains 69 amino acids, exists as dimers in solution, and tends to undergo reversible aggregation. The receptors of MIP-1alphain vivo are mainly the G-protein coupled receptors CCR1 and CCR5. Upon stimulation by endogenous and exogenous agents such as Interleukin-1beta, Interferon-gamma, and lipoteichoic acid from Gram-positive bacteria, monocytes are able to secrete significant amounts of MIP-1alpha. MIP-1alpha augments the adhesions of T lymphocytes, monocytes, and neutrophils to vascular cell adhesion molecule 1. In addition, in wounds, MIP-1alpha chemo-attracts macrophages in order to accelerate the tissue repair process. Recombinant human MIP-1 alpha/CCL3 (rhMIP-1 alpha) produced in E. coli is a single non-glycosylated polypeptide chain containing 70 amino acids. A fully biologically active molecule, rhMIP-1 alpha has a molecular mass of 7.8 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
Product Line	PL307_Cytokines, Chemokines & Growth Factors
Shipping Temperature	4
Storage Temperature	-65
Product Origin	USA

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Amount: 10ug

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Delivery expected until 5/16/2024