Comparison

Interleukin-17 Receptor C (IL-17 RC), His, Mouse European Partner

Item no. Z03329-50
Manufacturer GenScript
Amount 50 ug
Quantity options 10 ug 50 ug
Category
Type Proteins
Specific against Mouse (Murine, Mus musculus)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Available
Country of Origin
USA
Shipping Temperature
4°C
Storage Conditions
-80
Product Line
PL307_Cytokines, Chemokines & Growth Factors
Description
Interleukin-17 receptor C (IL-17RC) , also known as interleukin-17 receptor–like (IL-17RL), forms a heterodimeric complex with IL-17RA to engage IL-17 ligand and promote IL-17 signaling. IL-17RC has 22% sequence homology with IL-17RA and is highly expressed in epithelial cells. IL-17RC can undergo alternative splicing generating several different variants, some of which a function has yet to be defined. High expression of IL-17RC has been detected in prostate cancer cells, however, IL-17 signaling has also been show to promote anti-tumor activity in certain types of cancer. Due to IL-17’s role in inflammation, IL-17RC has been indicated as having a potential role in certain autoimmune disease.
Recombinant mouse IL-17RC produced in CHO cells is a polypeptide chain containing 451 amino acids. A fully biologically active molecule, rmIL-17RC has a molecular mass of 58 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques at GenScript.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50 ug
Available: In stock
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