Antibodies

MOUSE ANTI HUMAN CD65s

Manufacturer GENWAY
Category Products / Antibody
Type Antibody
Specific against Human
Applications IF
Amount 0.1 mg
Host Mouse
ArtNr 20-783-314626
Available
Genway ID:
GWB-558C3D
Specificity:
CD65s
Isotype:
IgM
Preparation:
Purified IgM prepared by ammonium sulphate precipitation.
Buffer Solution:
Phosphate buffered saline pH7. 4
Preservative Stabilisers:
0. 09% Sodium Azide (NaN3)Approx. Protein Concentrations: IgM concentration 1. 0mg/ml
Immunogen:
THP1 (human acute monocytic leukaemia cells)
Specificity:
Selectively recognises the sialylated form of human CD65 known as CD65s (VIM-2 antigen) a leucocyte carbohydrate antigen expressed by granulocytes monocytes and leukaemic cells of myelomonocytic lineage. CD65s is aberrantly expressed on some acute myeloid leukaemias (AML) and clone VIM-2 has been reliably used as a marker for distinguishing between mature and undifferentiated AML. During normal myelopoiesis expression of CD65s follows the disappearance of the progenitor antigen CD34. Cross-linking of the CD65s antigen using clone VIM-2 has been shown to induce phagocyte cytoplasmic calcium flux oxidative burst and degranulation (2). AbD Recommended Negative Controls: MOUSE IgM NEGATIVE CONTROLRecommended Secondary Antibodies: Goat Anti Mouse IgMGoat Anti Mouse IgG IgA IgMHuCAL Anti Mouse IgM
Amount: 0.1 mg
Available: In stock
Listprice: €274.04
Price: €274.04
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