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MOUSE ANTI HUMAN CD65s

MOUSE ANTI HUMAN CD65s

Manufacturer	GENWAY
Category	Antibodies Immunofluorescence Primary Antibodies
Type	Antibody
Specific against	Human
Applications	IF
Amount	0.1 mg
Host	Mouse
Item no.	20-783-314626
eClass 6.1	32160702
eClass 9.0	32160702
Available
Genway ID:	GWB-558C3D
Specificity:	CD65s
Isotype:	IgM
Preparation:	Purified IgM prepared by ammonium sulphate precipitation.
Buffer Solution:	Phosphate buffered saline pH7. 4
Preservative Stabilisers:		0. 09% Sodium Azide (NaN3)Approx. Protein Concentrations: IgM concentration 1. 0mg/ml
Immunogen:	THP1 (human acute monocytic leukaemia cells)
Specificity:	Selectively recognises the sialylated form of human CD65 known as CD65s (VIM-2 antigen) a leucocyte carbohydrate antigen expressed by granulocytes monocytes and leukaemic cells of myelomonocytic lineage. CD65s is aberrantly expressed on some acute myeloid leukaemias (AML) and clone VIM-2 has been reliably used as a marker for distinguishing between mature and undifferentiated AML. During normal myelopoiesis expression of CD65s follows the disappearance of the progenitor antigen CD34. Cross-linking of the CD65s antigen using clone VIM-2 has been shown to induce phagocyte cytoplasmic calcium flux oxidative burst and degranulation (2). AbD Recommended Negative Controls: MOUSE IgM NEGATIVE CONTROLRecommended Secondary Antibodies: Goat Anti Mouse IgMGoat Anti Mouse IgG IgA IgMHuCAL Anti Mouse IgM

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 5/30/2024