Comparison

MYCN Antibody (C-term)

Item no. ABC-AP7395b
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applications WB, IHC-P
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products MYCN, NMYC, bHLHe37, N-myc proto-oncogene protein, Class E basic helix-loop-helix protein 37, BHLHE37
Available
Primary Accession
P04198
Antigen Type
Synthetic Peptide
Application
WB, IHC-P
Bio Background
MYCN is a member of the MYC family and a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of its gene is associated with a variety of tumors, most notably neuroblastomas.
Bio References
Combaret, V., Pediatr Blood Cancer 53 (3), 329-331 (2009)
Alvarez-Rodriguez, R., J. Cell. Sci. 122 (PT 5), 595-599 (2009)
Jacobs, J.F., BMC Cancer 9, 239 (2009)
Clonality
Polyclonal
Clone/Animal Names
RB18771
Gene ID
4613
Gene Name
MYCN
Subtitle
Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
Anti-MYCN Antibody (C-term) at 1:1000 dilution + CCRF-CEM whole cell lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 50 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
Formalin-fixed and paraffin-embedded H.brain tissue reacted with MYCN Antibody (C-term) (Cat#AP7395b).
Type image 2
IHC-P
Dilution image 2
1:100
Other Accession
Q63379; P03966
Predicted
M, Rat
Isotype
Rabbit Ig
Calculated MW
49561
Antigen Region
322-351
Antigen Source
HUMAN
Target/Specificity
This MYCN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-351 amino acids from the C-terminal region of human MYCN.
NCBI Accession
NP_005369.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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