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IRS2 Antibody (C-term)

IRS2 Antibody (C-term)

Item no.	ABC-AP7789B
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies By Cell Type Carcinoma Hematology Lymphoma Immunohistochemistry Western Blot Immunofluorescence Endocrine Regulation of Lipid Metabolism Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IF, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Hagg,D.A., Int. J. Mol. Med. 21 (6), 697-704 (2008) Platanias,L.C., J. Biol. Chem. 271 (1), 278-282 (1996) Sun,X.J., Nature 377 (6545), 173-177 (1995)
NCBI	NP_003740.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Insulin receptor substrate 2,IRS-2,IRS2
Similar products	IRS-2, IRS2, Insulin receptor substrate 2
Available
Manufacturer - Category	Crown Antibodies; Primary Antibodies; Cardiovascular; Metabolism; Signal Transduction; Interleukin signaling
Manufacturer - Targets	This IRS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1309-1338 amino acids from the C-terminal region of human IRS2.
Bio Background	Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB15641
Gene Name	IRS2
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	137334
Antigen Source	HUMAN
Antigen Region	1309-1338
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	IF: 1:10~50 WB: 1:1000 WB: 1:1000 IHC-P: 1:50~100
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 12/4/2025

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