CCR3 Antibody (Center)

Primary Antibodies; Antibody Collections; Immunology; Signal Transduction; GPCR Antibodies; Druggable G protein-coupled receptors (GPCRs); Viral process; Host-virus interaction; Immune system process; Chemokine receptor family; Chemokine signaling; Inflammation mediated by chemokine and cytokine signaling

CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1.

RB22038

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Pr

HUMAN

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Synthetic Peptide