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Vorinostat

Vorinostat

Item no.	HY-10221-100mg
Manufacturer	MedChem Express
CASRN	149647-78-9
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 1 g 250 mg 500 mg 5 g
Specific against	other
Purity	99.96
Smiles	O=C(NC1=CC=CC=C1)CCCCCCC(NO)=O
Alias	SAHA,Suberoylanilide hydroxamic acid
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Apoptosis; Autophagy; Filovirus; HDAC; HPV; Mitophagy
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	264.32
Product Description	Vorinostat (SAHA) is a potent and orally active pan-inhibitor of HDAC1, HDAC2 and HDAC3 (Class I), HDAC6 and HDAC7 (Class II) and HDAC11 (Class IV), with ID50 values of 10 nM and 20 nM for HDAC1 and HDAC3, respectively. Vorinostat induces cell apoptosis[1][4]. Vorinostat is also an effective inhibitor of human papillomaviruse (HPV)-18 DNA amplification[7].
Manufacturer - Research Area	Cancer; Infection
Solubility	DMSO : ≥ 100 mg/mL
Manufacturer - Pathway	Anti-infection; Apoptosis; Autophagy; Cell Cycle/DNA Damage; Epigenetics
Clinical information	Launched
Isoform	HDAC1; HDAC11; HDAC2; HDAC3; HDAC7

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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HY-10221-100mg-safety-datasheet.pdf