SCR7

Item no.	HY-12742-1mg
Manufacturer	MedChem Express
CASRN	1533426-72-0
Amount	1 mg
Quantity options	10 mMx1 mL 10 mg 1 ea 1 mg 25 mg 50 mg 5 mg
Specific against	other
Purity	98.22
Smiles	O=C(N1)C(/N=C/C2=CC=CC=C2)=C(NC1=S)/N=C/C3=CC=CC=C3
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	Apoptosis; CRISPR/Cas9; DNA/RNA Synthesis
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	334.39
Product Description	SCR7 is an unstable form that can be autocyclized into a stable form SCR7 pyrazine (HY-107845). SCR7 pyrazine is a DNA ligase IV inhibitor that blocks nonhomologous end-joining (NHEJ) in a ligase IV-dependent manner. SCR7 pyrazine increases the efficiency of Cas9-mediated homology-directed repair (HDR). SCR7 pyrazine induces cell apoptosis and has anticancer activity[1][2].
Manufacturer - Research Area	Cancer
Solubility	DMSO : ≥ 45 mg/mL
Manufacturer - Pathway	Apoptosis; Cell Cycle/DNA Damage
Clinical information	No Development Reported

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