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Infigratinib

Infigratinib

Item no.	HY-13311-1g
Manufacturer	MedChem Express
CASRN	872511-34-7
Amount	1 g
Quantity options	100 mg 10 mM/1 mL 10 mg 1 g 1 mg 200 mg 25 mg 500 mg 50 mg 5 mg
Specific against	other
Purity	99.82
Smiles	ClC1=C(C(Cl)=C(C=C1OC)OC)NC(N(C2=CC(NC3=CC=C(C=C3)N4CCN(CC4)CC)=NC=N2)C)=O
Alias	BGJ-398,NVP-BGJ398
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	Apoptosis; FGFR
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	560.48
Product Description	Infigratinib (BGJ-398; NVP-BGJ398) is a potent inhibitor of the FGFR family with IC50s of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively.
Manufacturer - Research Area	Cancer
Solubility	DMSO : 12 mg/mL (ultrasonic)\|H2O : < 0.1 mg/mL (ultrasonic)
Manufacturer - Pathway	Apoptosis; Protein Tyrosine Kinase/RTK
Clinical information	Launched

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