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Alpelisib

Alpelisib

Item no.	HY-15244-1g
Manufacturer	MedChem Express
CASRN	1217486-61-7
Amount	1 g
Quantity options	100 mg 10 mM/1 mL 10 mg 1 g 200 mg 500 mg 50 mg 5 mg
Specific against	other
Purity	99.95
Smiles	CC(N=C(S1)NC(N2CCC[C@H]2C(N)=O)=O)=C1C3=CC(C(C)(C(F)(F)F)C)=NC=C3
Alias	BYL-719
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-Kinase/protease
Manufacturer - Targets	PI3K
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	441.47
Product Description	Alpelisib (BYL-719) is a potent, selective, and orally active PI3Kα inhibitor. Alpelisib (BYL-719) shows efficacy in targeting PIK3CA-mutated cancer. Alpelisib (BYL-719) also inhibits p110α/p110γ/p110δ/p110β with IC50s of 5/250/290/1200 nM, respectively. Antineoplastic activity[1][2][3].
Manufacturer - Research Area	Cancer
Solubility	DMSO : 83.33 mg/mL (ultrasonic)
Manufacturer - Pathway	PI3K/Akt/mTOR
Clinical information	Launched
Isoform	PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ

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