Comparison

GR 113808 European Partner

Manufacturer MedChem Express
Category
Type Inhibitors
Specific against other
Amount 25mg
Item no. HY-103152-25mg
CASRN 144625-51-4
Available
Product Description
GR 113808 is a potent and highly selective 5-HT4 receptor antagonist (pKb= 8.8). GR 113808 shows 300-fold selectivity over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors.
StorageTemperature
-20°C, sealed storage, away from moisture; In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Applications
COVID-19-immunoregulation
Formula
C19H27N3O4S
References
[1].Gale JD, et al. GR113808: a novel, selective antagonist with high affinity at the 5-HT4 receptor.Br J Pharmacol. 1994 Jan; 111(1):332-8. | [2].Spohn SN, et al.Protective Actions of Epithelial 5-Hydroxytryptamine 4 Receptors in Normal and Inflamed Colon.Gastroenterology. 2016 Nov; 151(5):933-944.e3.
MolecularWeight
393.5
Research Area
Inflammation/Immunology; Neurological Disease
Solubility
DMSO : 39 mg/mL (99.11 mM; Need ultrasonic and warming)
Target
5-HT Receptor
Isoform
5-HT4 Receptor; 5-HT1A Receptor; 5-HT3 Receptor; 5-HT2A Receptor; 5-HT2C Receptor
Pathway
GPCR/G Protein; Neuronal Signaling

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

Amount: 25mg
Available: In stock
available

Delivery expected until 4/6/2023 

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