MeBIO

Manufacturer	MedChem Express
Category	Inhibitors
Type	Inhibitors
Specific against	other
Amount	10mg
Item no.	HY-103221-10mg
CASRN	667463-95-8
Available
Product Description	MeBIO is a potent AhR (aryl hydrocarbon receptor) agonist, with IC50 of 44 μM (GSK-3) and 55 μM (CDK1/cyclin B), respectively. MeBIO is inactive on GSK-3β.
StorageTemperature	Powder -20°C 3 years, 4°C 2 years; In solvent -80°C 6 months, -20°C 1 month
Applications	COVID-19-anti-virus
Formula	C17H12BrN3O2
References	[1].Meijer L, et al. GSK-3-selective inhibitors derived from Tyrian purple indirubins. Chem Biol. 2003 Dec; 10(12):1255-66.
MolecularWeight	370.2
Research Area	Others
Solubility	DMSO : 14.71 mg/mL (39.74 mM; ultrasonic and warming and heat to 60°C)
Target	Aryl Hydrocarbon Receptor; GSK-3; CDK
Isoform	GSK-3; Cdk1/cyclin B; Cdk5/p25
Pathway	Immunology/Inflammation; PI3K/Akt/mTOR; Stem Cell/Wnt; Cell Cycle/DNA Damage

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Amount: 10mg

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Delivery expected until 4/20/2023

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